Chapter 279 — सिद्धौषधानि (Siddhauṣadhāni, “Perfected Medicines”) — Colophon/Closure
आदिमध्यावसानेषु कफपित्तसमीरणाः प्रकोपं यान्ति कोपादौ काले तेषाञ्चयः स्मृतः
ādimadhyāvasāneṣu kaphapittasamīraṇāḥ prakopaṃ yānti kopādau kāle teṣāñcayaḥ smṛtaḥ
ஆரம்பம், நடு, முடிவு ஆகிய காலங்களில் கபம், பித்தம், சமீரணம் (வாதம்) தீவிரமடைகின்றன; அந்தத் தீவிரக் காலத்தின் தொடக்கத்தில் அவற்றின் சேர்க்கை (சஞ்சயம்) நிகழும் என்று கூறப்படுகிறது।
Lord Agni (Agni Purana narrator) to Sage Vasiṣṭha (traditional dialogue frame)
Primary Rasa: adbhuta
Secondary Rasa: shanta
Sandhi Resolution Notes: आदिमध्यावसानेषु = आदि + मध्य + अवसानेषु; कफपित्तसमीरणाः dvandva; कोपादौ = कोप + आदौ; तेषाञ्चयः = तेषाम् + चयः (sandhi: m + c → ñc).
Ayurvedic diagnostic knowledge: it states the time-pattern of doṣas—kapha, pitta, and vāta—showing that doṣas first accumulate (saṃcaya) at the onset of a period and then become aggravated (prakopa) across its phases.
It demonstrates that the Agni Purana is not only mythic and ritualistic but also preserves applied medical theory (Ayurveda), including technical doṣa dynamics used for prevention, diagnosis, and timing of therapies.
By encouraging disciplined, time-appropriate conduct that prevents doṣa aggravation, the verse supports sāttvic living and bodily purity—conditions traditionally regarded as conducive to dharma, worship, and steady spiritual practice.